Eurasian Journal of Chemical, Medicinal and Petroleum Research

Abstract Introduction: Pregnancy-related hormonal and vascular changes may increase nasal mucosal congestion, particularly during the third trimester, when sleep disturbance is also common. Nasal obstruction can promote mouth breathing, nocturnal discomfort, and fragmented sleep. This study aimed to evaluate the effect of NOSE score on sleep quality in primigravid women during the third trimester of pregnancy.

Material and methods: This descriptive cross-sectional study will be conducted at Tabriz University of Medical Sciences in 2026 on 66 primigravid women in the third trimester of pregnancy, selected by convenience sampling. The main variables will include demographic and obstetric characteristics, NOSE score, sleep quality indices, and pregnancy-related sleep disruptors such as nocturia, reflux, back pain, fetal movement-related awakening, and nocturnal breathing discomfort.

Results: Among 66 primigravid women, poor sleep quality was associated with significantly higher NOSE scores than good sleep quality (56.84 ± 18.27 vs. 31.46 ± 14.92, p < 0.001), with severe nasal obstruction occurring more often in poor sleepers (39.47% vs. 10.71%, p = 0.012). NOSE score correlated with worse sleep quality (r = 0.58, p < 0.001) and remained an independent predictor in adjusted analysis (B = 0.07, p = 0.001).

Conclusion: Poor sleep quality in third-trimester primigravid women was significantly associated with greater nasal obstruction severity. Higher NOSE scores independently predicted worse sleep quality, suggesting that nasal symptoms may represent an important and potentially modifiable contributor to sleep disturbance during late pregnancy.

Abstract Introduction: Nasal bone fracture is a common facial injury with potential early postoperative consequences, including pain, bleeding, edema, airway symptoms, and residual deformity. Fracture severity may influence these outcomes by reflecting the extent of structural and soft-tissue damage. This study aimed to determine short-term postoperative complications according to nasal bone fracture severity.

Material and methods: This descriptive cross-sectional study of 75 patients at Tabriz University of Medical Sciences in 2024 investigated the association between nasal bone fracture severity and early outcomes. Measured variables included demographics, fracture characteristics, surgical parameters, and short-term complications, including VAS pain score, epistaxis, edema, ecchymosis, and septal hematoma. Data were analyzed using normality testing, t-tests, Mann-Whitney U, and chi-square tests.

Results: Among 75 patients, severe/complex nasal fractures (n = 34) were associated with worse short-term postoperative outcomes than mild/moderate injuries (n = 41). Severe fracture patients experienced longer operations (41.53 ± 11.47 vs. 28.64 ± 8.12 minutes, p < 0.001), higher 24-hour VAS pain (4.85 ± 1.56 vs. 3.42 ± 1.18, p < 0.001), increased moderate/severe edema (61.76% vs. 26.83%, p = 0.002), and more unplanned visits (26.47% vs. 7.32%, p = 0.027). Severe fracture independently predicted early complications (adjusted OR = 3.86, p = 0.020).

Conclusion: Severe nasal bone fractures are independently associated with an increased risk of short-term postoperative complications. Patients with complex fracture patterns experience higher pain levels, more pronounced soft-tissue edema, and greater rates of early residual deformity, leading to more frequent unplanned clinical evaluations. Preoperative severity stratification can identify high-risk cases requiring closer early postoperative surveillance.