Medicine
Parisa Mehrasa; Tala Pourlak
Abstract
Introduction: This is because the development of cytokine release syndrome (CRS) as the pathologic basis for the progression of severe Covid-19 disease is possible. Material and Methods: A two-step selection process that involved first screening studies based on their titles and abstracts and then reading ...
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Introduction: This is because the development of cytokine release syndrome (CRS) as the pathologic basis for the progression of severe Covid-19 disease is possible. Material and Methods: A two-step selection process that involved first screening studies based on their titles and abstracts and then reading the full texts of those studies was carried out independently by the two reviewers. Studies were considered if they were RCTs, observational cohorts, or case-control in design, described two or more patients diagnosed with Covid19, and reported measures of cytokine levels (with a focus on IL-6). The use of standardized data extraction tables allowed for the duplication of the data extraction process. Data were taken from the text of the article, the tables, and the graphs.Results: In all of the studies that were included, elevated IL-6 levels were found in Covid-19 patients. Numerous studies specifically found that patients with more severe (complicated) diseases had higher levels of IL-6 descriptions of other inflammatory markers, such as ferritin and IL2R. Six studies in total compared the levels of IL-6 in patients with complicated disease (those with ARDS, needing ICU admission, or having "severe" or "critical" presentations according to the Chinese New Coronavirus Pneumonia Prevention and Control Program score) and noncomplicated disease (those without the aforementioned criteria present).Conclusion: In this systematic review and meta-analysis, we show that elevated serum IL-6 levels are associated with complicated Covid 19 disease and that these elevated IL-6 levels are also significantly associated with poor clinical outcomes. This implies that an excessive host immune response and autoimmune injury may be the result of an initial SARS-CoV2 infection that progresses to a complicated disease. These results underline the necessity of continuing, carefully designed clinical studies to clarify the function of immunomodulation, specifically IL-6 inhibition, in the treatment of severe Covid-19.
Medicine
Salar Javanmard Barbin; Negar Javanmard Barbin; Arash Dastshosteh; Mohammad Mahdi Nemati; Shiva Heidari
Abstract
The relationship between awareness and physical and mental health of people is direct and strong and is significant at the 95% confidence level. Since the Covid-19 disease is more effective on people with underlying diseases, therefore, if a person suffers from a chronic disease, it can make him sicker ...
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The relationship between awareness and physical and mental health of people is direct and strong and is significant at the 95% confidence level. Since the Covid-19 disease is more effective on people with underlying diseases, therefore, if a person suffers from a chronic disease, it can make him sicker and therefore the person has less desire to get information about this disease, which reduces the level of awareness. and this issue is also true in relation to intellectual obsessions. In such a way that students with phobia or any other mental disorder deal with the subject more carefully. On the other hand, high awareness in people reduces the amount of stress related to the disease and improves the level of mental health and subsequently physical health. The results of this research also showed that the relationship between attitude and physical and mental health of people is direct but relatively weak, although it is significant at the 95% confidence level. Although mental and physical health increases the level of awareness, it does not have an effect on a person's perspective of an existing reality.
Covid
Dinami.H Birman
Abstract
This study investigated the effects of Covid-19 on body postures. Specialists around the world are now conducting clinical trials and research to understand why some patients recovering from Covid-19 have long-term complications. The coronavirus primarily affects the respiratory system and can cause ...
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This study investigated the effects of Covid-19 on body postures. Specialists around the world are now conducting clinical trials and research to understand why some patients recovering from Covid-19 have long-term complications. The coronavirus primarily affects the respiratory system and can cause pneumonia and endanger human life. Other research shows that the disease can cause blood clots and inflammation in many parts of the body, and even in mild cases. Covid-19 can also be seen. This indicates the great need to take care of yourself against the disease. The recovery time from Covid-19 disease varies from person to person. Many people feel better in a few days or weeks, and most will recover within 12 weeks, but in some people, the symptoms may last longer. The likelihood of long-term symptoms does not appear to be related to how the disease occurred when you first contracted the coronavirus, and people who have experienced mild Covid-19 may also have long-term symptoms. The corona virus, especially its newer form, the delta corona, does not only attack the lungs; The heart, kidneys, brain, arteries, nerves, and skin are other organs that have been shown to affect the function of a new mutation in the Covid-19 virus.
Covid
Stephan Birmangi
Abstract
Infection with the corona virus leads to short-term and long-term effects, which sometimes affect the sufferers for the rest of their lives. The effect of Corona on the human brain has been studied by many scientists. The new symptoms that have been observed in patients suffering from the disease of ...
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Infection with the corona virus leads to short-term and long-term effects, which sometimes affect the sufferers for the rest of their lives. The effect of Corona on the human brain has been studied by many scientists. The new symptoms that have been observed in patients suffering from the disease of Covid-19 indicate the effect of the corona virus on the functioning of the human brain and nervous system. While examining and treating patients in New York, which is considered to be the most prominent state in America in terms of infection with the corona virus and the number of victims of the Covid-19 disease, apart from fever, cough, body pain and shortness of breath, new signs of the destructive effect of the corona virus on human health. They found that the brain and nervous system of the patients are also somehow involved in this disease. Among the characteristics of this new finding is confusion, forgetfulness and even convulsions caused by nervous pressure in patients with Covid-19, many cases of which have been observed in New York state; In such a way that some patients do not even know where they are and why they are in the hospital or what year we are in now. In most cases, these symptoms are related to the lack of oxygen in the blood; However, it has been observed that this memory disorder in some patients is not very proportional due to the level of pulmonary involvement with the virus. "Jennifer Frontera", a neurologist at Langone University Hospital in Brooklyn, one of the old parts of New York City, believes that according to the new findings, the issue of involvement of the brain and nervous system when contracting the new type of corona virus is now seriously discussed in it has been investigated.
