Eurasian Journal of Chemical, Medicinal and Petroleum Research

Abstract The present study examined clinical and neurological problems and clinical tests in Alzheimer's patients specializing in Alzheimer's disease. The cause of Alzheimer's disease is the deposition of a series of proteins called amyloid and tau outside or inside brain cells, which occurs by creating plaques or knots in these cells. This begins before the onset of symptoms, and fortunately, this factor makes it possible to diagnose the disease before the onset of symptoms with special devices. Clinical and neurological problems and clinical tests in Alzheimer's patients are of great importance. Over time, with the deposition of these proteins in the brain, the level of neurotransmitters in the brain decreases sharply and various areas in the brain begin to shrink. The results showed that the first area of the brain to be affected is usually the memory area, but it is possible that the visual or speech and language areas of the brain may also be damaged over time. Another factor that increases the severity of this disease is aging, with some studies showing that the risk of developing Alzheimer's doubles for every five years after the age of 65. A family history of dementia, such as Parkinson's, down syndrome, severe brain injury, a sedentary lifestyle, hearing loss, depression, and heart problems are among the factors that increase a person's risk of developing this condition.

Abstract Introduction: Alzheimer's disease is a brain disorder that causes the brain to shrink and eventually die brain cells. The present study systematically reviewed neurological problems and stress in Alzheimer's patients with drug tips.

Materials and methods: An extensive search strategy was developed for literatures by 50 article. To obtain scientific evidence related to the prevalence of old age sufferings in the elderly in Iran from articles published in interior and foreign databases such as Scientific Information Database (SID), Magiran, Web of Science, Psyc INFO, PubMed, Scopus, and Google Scholar search engine were used. All articles, regardless of the time period, were searched in the databases until September 2024. PRISMA 2020 checklist was used in order to screen articles, extract data and brief related findings.

Results: The most common symptoms of Alzheimer's are forgetting recent events or conversations and difficulty remembering newly learned information. Over time, memory problems become more severe and the person eventually loses the ability to perform daily tasks. After a while, patients usually have difficulty finding the right words to express their thoughts and will need more time to complete routine daily tasks. Some brain imaging tests can detect protein deposits called amyloid in the brain, allowing treatment before the onset of major symptoms.

Conclusion: Dementia also affects other body systems, such as breathing. For example, as the gray matter of the brain deteriorates and the person loses the ability to perform certain voluntary actions, such as moving the diaphragm, the patient becomes susceptible to diseases such as pneumonia, which shortens their lifespan. Therefore, it is not possible to make a definitive judgment about the lifespan of a person with Alzheimer's.