Eurasian Journal of Chemical, Medicinal and Petroleum Research

Abstract Introduction: Nasal bone fracture is a common facial injury with potential early postoperative consequences, including pain, bleeding, edema, airway symptoms, and residual deformity. Fracture severity may influence these outcomes by reflecting the extent of structural and soft-tissue damage. This study aimed to determine short-term postoperative complications according to nasal bone fracture severity.

Material and methods: This descriptive cross-sectional study of 75 patients at Tabriz University of Medical Sciences in 2024 investigated the association between nasal bone fracture severity and early outcomes. Measured variables included demographics, fracture characteristics, surgical parameters, and short-term complications, including VAS pain score, epistaxis, edema, ecchymosis, and septal hematoma. Data were analyzed using normality testing, t-tests, Mann-Whitney U, and chi-square tests.

Results: Among 75 patients, severe/complex nasal fractures (n = 34) were associated with worse short-term postoperative outcomes than mild/moderate injuries (n = 41). Severe fracture patients experienced longer operations (41.53 ± 11.47 vs. 28.64 ± 8.12 minutes, p < 0.001), higher 24-hour VAS pain (4.85 ± 1.56 vs. 3.42 ± 1.18, p < 0.001), increased moderate/severe edema (61.76% vs. 26.83%, p = 0.002), and more unplanned visits (26.47% vs. 7.32%, p = 0.027). Severe fracture independently predicted early complications (adjusted OR = 3.86, p = 0.020).

Conclusion: Severe nasal bone fractures are independently associated with an increased risk of short-term postoperative complications. Patients with complex fracture patterns experience higher pain levels, more pronounced soft-tissue edema, and greater rates of early residual deformity, leading to more frequent unplanned clinical evaluations. Preoperative severity stratification can identify high-risk cases requiring closer early postoperative surveillance.

Abstract Background: The Systemic Immune-Inflammation Index (SII) has emerged as a reliable marker of systemic inflammation and has been associated with various postoperative outcomes in surgical patients. However, its relationship with acute postoperative pain in patients undergoing hip arthroplasty for femoral fractures remains underexplored. Objective: This study aims to investigate the correlation between the SII and acute pain intensity in patients undergoing hip arthroplasty for femoral fractures, along with its association with postoperative clinical outcomes such as length of hospital stay (LOHS), ICU admission, and platelet count.

Methods: This prospective observational study was conducted with 112 patients who underwent hip arthroplasty for femoral fractures. Preoperative blood samples were used to calculate the SII, and pain intensity was measured at various time points postoperatively using a visual analog scale (VAS). Clinical outcomes, including LOHS, ICU admissions, and platelet counts, were recorded.

Results: A significant positive correlation was found between the SII and postoperative pain intensity, with higher SII values associated with increased pain levels at 2 and 4 hours postoperatively (r = +0.745, p = 0.005). Additionally, patients with elevated SII values had significantly longer hospital stays (22 days vs. 17 days, p = 0.006), higher ICU admission rates (27.94% vs. 16.60%, p = 0.036), and elevated platelet counts. The SII was also significantly correlated with neutrophil and lymphocyte counts, highlighting its role in reflecting the inflammatory response.

Conclusion: The SII appears to be a promising predictor of postoperative pain intensity and adverse clinical outcomes in patients undergoing hip arthroplasty for femoral fractures. Elevated SII values are associated with increased pain, prolonged hospital stays, and higher rates of ICU admission. These findings suggest that the SII could serve as a useful biomarker for assessing postoperative complications and guiding clinical management in surgical patients.