Document Type : Original Article
Authors
1 10th grade student of Salam Golbang High School, Tehran, Iran.
2 Specialist Assistant in Veterinary Pathology, Faculty of Veterinary Specialized Sciences, Islamic Azad University, Research Sciences Unit, Tehran, Iran
Abstract
Graphene oxide (GO) produced by intense oxidation of graphite in Hamer method is an ideal nano carrier for drug and gene delivery. The number of graphene oxide layers used for drug delivery is between one and three layers (the total thickness of the layers is 1 to 2 nm) and their size is between a few nanometers and several hundred nanometers. This material has unique structural features such that its specific contact surface is very high (2630 square meters per gram) and on the other hand, it is full of oxygen-rich groups; For this reason, this two-dimensional material has good biocompatibility and physiological solubility, and its stability is also suitable. The mentioned characteristics have made this material a suitable option for loading drugs and genes through chemical correlation. The presence of hydroxyl (OH) and carboxyl (COOH) functional groups in the structure of graphene oxide has caused GO to have good correlation with various systems such as polymers, biomolecules, quantum dots, iron oxide nanoparticles (Fe3O4), etc. It is possible to predict various applications for graphene oxide in this field used graphene oxide for water-insoluble aromatic anticancer drugs.
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