Process mixers and reactors are customized equipment with different capabilities that are designed and built for different pressure and temperature conditions according to process requirements. This equipment is available in atmospheric, pressure and vacuum, single-wall, double-wall and triple-wall types. The design and construction of these mixers is based on the latest standard editions of the American Society of Mechanical Engineers (ASME) and the use of up-to-date mixer technology and the creativity of the creativity of experienced mechanical engineers and (Pharmaceutical Equipment Department of mechanical engineers group - Petromana). According to the needs of these mixers and reactors, they can be used in various chemical, food, sanitary, cosmetic and pharmaceutical industries. Also, considering the necessary requirements in designing and manufacturing, injectable drugs are also widely used. All types of reactors and fermenters can be produced in the family of these products. All industrial mixers have a mechanism similar to a simple household device, they all have a power generator, power transmission, blades and a container for storing materials. Only in some types, the blade type changes depending on the ingredients that are to be mixed. The material input is a constant flow, just like a river with a very calm surface and a very turbulent depth. The liquid surface remains constant and does not mix well. In this situation, we have no choice but to change the type of blade. The available options are to design the same shaft in the liquid surface and increase the number according to the need and length of the shaft, for example, design the same shaft in the middle of the liquid, but what if the liquid becomes denser and thicker? In this study, hybrid mixers have been investigated.