Effects of laparoscopic abdominal surgery on pulmonary function and arterial blood gas parameters of smoking patients

Zamiri, Reza Eghdam; Aghdam, Abdolreza Mehdinavaz

doi:10.5281/zenodo.8322259

Effects of laparoscopic abdominal surgery on pulmonary function and arterial blood gas parameters of smoking patients

Document Type : Original Article

Authors

Reza Eghdam Zamiri ¹

Abdolreza Mehdinavaz Aghdam ²

¹ Associate Professor of Radiology, Department of Radiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

² Assistant Professor of Surgery, Department of General Surgery, Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

https://doi.org/10.5281/zenodo.8322259

Abstract

Introduction: moking increases the risk of postoperative pulmonary complications in patients receiving general anesthesia. During laparoscopic surgeries, the effects of pneumoperitoneum and carbon dioxide (CO2) insufflation may amplify these. Our goal was to compare the metabolic and blood gas analysis of patients who underwent laparoscopic surgeries while under general anesthesia compared to those who did not smoke.

Material and Methods: After receiving approval from the institutional review board, the 60 patients undergoing laparoscopic cholecystectomy were split into two groups of 30 each: smokers and non-smokers. A arterial blood gas sampling was performed along with baseline hemodynamic parameters to evaluate and compare PCO2, pH, and bicarbonate (HCO3) values at different time intervals with respect to pneumo-peritoneum creation, between smokers and non-smokers.

Results: Systolic blood pressure was higher at baseline in the smoker group, and oxygen saturation was noticeably lower. Smokers had significantly higher PCO2 and end-tidal CO2 at all times

Conclusion: Between smokers and non-smokers, there is a clear distinction in baseline arterial blood gas characteristics. Smokers appear to be more susceptible to the metabolic effects of CO2 insufflation and elevated intraabdominal pressure.

Keywords

Blood gas analysis

laparoscopic surgery

pneumoperitoneum

smoking

Subjects