Document Type : Original Article


1 Associated Professor of Anesthesiology, Department of Anesthesiology, Medicine Faculty, Tabriz University of Medical Sciences Tabriz, Iran

2 Assistant Professor of Orthopaedics, Department of Orthopedics, School of Medicine, Shohada Medical Research & Training Hospital, Tabriz University of Medical Sciences, Tabriz, Iran


Introduction: This systematic review will contribute to the existing body of knowledge by synthesizing the available evidence regarding the effects of morphine injection during anesthesia on hemodynamic status and acute pain intensity after tibia plate implantation surgeries in the elderly. The findings may have implications for perioperative pain management strategies, ultimately leading to improved patient outcomes and enhanced quality of care for this vulnerable patient population.

Material and Methods: Data extraction will be performed independently by two reviewers using a standardized data extraction form. The extracted data will include study characteristics (author, publication year, country), study design, sample size, patient demographics (age, gender), intervention details (morphine dosage, timing of administration), comparison groups, outcome measures assessed, follow-up duration, and relevant statistical analyses.

Results: The results of this analysis revealed that higher doses of morphine were associated with more pronounced effects on hemodynamic parameters, including a greater decrease in MAP and heart rate.

Conclusion: this systematic review suggests that morphine injection during anesthesia may have favorable effects on hemodynamic stability and acute pain intensity in elderly patients undergoing tibia plate implantation surgeries. The administration of morphine during anesthesia appears to reduce blood pressure and heart rate fluctuations and provide effective analgesia in the immediate postoperative period.


Main Subjects