Medicine
Mohammad Irajian; Vahid Fattahi
Abstract
Introduction: Regional anesthesia is considered an important tool in postoperative pain management while minimizing opioid use. However, post-operative recovery (characterized by peripheral nerve hyperalgesia) may reduce or completely block the effect of this change, since opioids may act better after ...
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Introduction: Regional anesthesia is considered an important tool in postoperative pain management while minimizing opioid use. However, post-operative recovery (characterized by peripheral nerve hyperalgesia) may reduce or completely block the effect of this change, since opioids may act better after the blockage is removed.Material and Methods: This study was a systematic Review. We reviewed the published literature describing the pathophysiology and development of complications after peripheral artery dissection in orthopedic surgery patients. Search for related articles using PubMed, EMBASE, and Web of Science.Results: We included 28 articles (n=28) in our review. Perioperative peripheral nerve considerations and other postoperative pain management for orthopedic surgery patients are discussed. Multimodal strategies such as preemptive analgesia, intra-articular or intravenous anti-inflammatory drugs, and adjuvants in vain block fluid before block failure will reduce the burden of rebound pain.Conclusion: Additionally, educating the patient about the possibility of back pain is important to ensure proper use of pain relievers and to reduce the need for pain relief opioids. Understanding the effects of relapse and prevention of relapse is important to reduce the side effects associated with the use of opioids for regional anesthesia.
Medicine
Mohammad Irajian; Vahid Fattahi
Abstract
Introduction: Most patients experience moderate to severe pain after ankle surgery. Early and appropriate treatment of postoperative pain is essential for effective treatment that leads to preservation of lung function, normal breathing, rehabilitation and prevention of chronic pain. In this retrospective ...
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Introduction: Most patients experience moderate to severe pain after ankle surgery. Early and appropriate treatment of postoperative pain is essential for effective treatment that leads to preservation of lung function, normal breathing, rehabilitation and prevention of chronic pain. In this retrospective study, we aimed to identify potential predictors of moderate-to-severe postoperative pain in the post-anesthesia care unit (PACU) in patients undergoing gastric bypass surgery.Material and Methods: In this systematic review VAS/vNRS score of 4-6 is considered moderate, and 7-10 is considered severe. Additional factors investigated included time from ankle fracture to surgery, anesthesia procedure, preoperative anesthesia, medication use and postoperative medication use, classification radiation, bone complexity, surgical technique, and tourniquet operative time.Results: Data from 336 patients who underwent ankle arthroplasty between January 2009 and December 2022 were analyzed. None of the following variables had a significant effect on pain; age, weight, smoking, time from fracture to surgery, type of anesthesia, opioids to control dysfunction, complexity of the fracture, surgical procedure or tourniquet technique increase. Gender predicted moderate to severe pain after PACU by 2 differences.31 (1.39–3.86, P = 0.001). To our knowledge, this is the first study to report gender differences in pain reporting in the hours following joint surgery.Conclusion: Female patients who had surgery for ankle sprains reported higher pain scores in the PACU than men.
Medicine
Abdolreza Mehdinavaz Aghdam; Fariborz Rousta
Abstract
Introduction: The objective of the study was to assess and compare the analgesic effectiveness and safety profiles of pethidine in relieving pain experienced post major surgical procedures. Material And Methods: A prospective interventional investigation was carried out on a cohort of 71 patients who ...
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Introduction: The objective of the study was to assess and compare the analgesic effectiveness and safety profiles of pethidine in relieving pain experienced post major surgical procedures. Material And Methods: A prospective interventional investigation was carried out on a cohort of 71 patients who underwent a significant surgical procedure. In this study, a total of 71 patients were administered intramuscular medication for a duration of 48 hours following surgery. Specifically, 36 individuals were treated with placebo dosages of 3 CC administered at 6-hour intervals, whereas the remaining 35 received 100 mg doses of pethidine at the same frequency. The present study aimed to evaluate and compare the analgesic efficiency and safety of placebo and pethidine. The aforementioned evaluation was performed at various time intervals of 1, 6, 12-, 24-, 32-, and 48-hours post-administration of the respective drugs. The efficacy of analgesics was evaluated through the utilization of both the Visual Analogue Scale (VAS) and Verbal Rating Scale (VRS). Results: The present study demonstrated the equianalgesic efficacy between placebo and Pethidine as determined by both Visual Analogue Scale (VAS) scores at 12 and 48 hours, and Verbal Rating Scale (VRS) scores at 1 and 48 hours during the postoperative period. During alternative observation periods, it was observed that pethidine demonstrated superior analgesic properties when compared to ketorolac. Conclusion: Pethidine demonstrated a higher degree of efficacy as an analgesic agent in comparison to ketorolac. Additional investigations, comprising a double-blind randomized trial, have been proposed to authenticate the findings presented in the current undertaking.
