Document Type : Original Article


1 Ali Reza Lotfi: Associate Professor of Otorhinolaryngology, Head and Neck Surgery, Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

2 2Assistant Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.


Introduction: Pain intensity represents an important but understudied aspect of sinonasal mucormycosis surgery. Understanding the relationship between pain intensity and mortality is crucial for optimizing pain management strategies and improving patient outcomes.

Material and Methods: Data collection was conducted by reviewing electronic medical records and surgical databases to extract relevant information on patient demographics, clinical characteristics, surgical procedures, pain intensity scores, and mortality outcomes. Pain intensity scores were assessed using validated pain assessment tools such as the Numerical Rating Scale (NRS) or Visual Analog Scale (VAS).

Results: The results of the multivariable Cox proportional hazards regression analysis revealed that pain intensity was significantly associated with mortality (HR: 1.82, 95% CI: 1.45 - 2.28, p < 0.001). After adjusting for age, comorbidities, and surgical procedures, each unit increase in pain intensity was associated with a 1.82-fold increase in the hazard of mortality

Conclusion: Our study highlights the significant association between pain intensity and mortality following sinonasal mucormycosis surgery. Effective pain management plays a crucial role in optimizing outcomes for patients undergoing surgical treatment for mucormycosis, and efforts to improve pain control should be integrated into perioperative care protocols.


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