Investigation of Antibiotic Resistance Patterns of Bacteria Isolated from Blood, Urine, and Respiratory Secretions in Hospitalized Patients in the Neurology Departments

Charsouei, Saeid; Osquee, Hamid Owaysee

Investigation of Antibiotic Resistance Patterns of Bacteria Isolated from Blood, Urine, and Respiratory Secretions in Hospitalized Patients in the Neurology Departments

Document Type : Original Article

Authors

Saeid Charsouei ¹

Hamid Owaysee Osquee ²

¹ Associate Professor of Neurology, Department of Neurology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

² Associate Professor of Infectious Disease, Department of Infectious Disease, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Background: Antibiotic resistance is a critical concern in healthcare, particularly among hospitalized patients in neurology departments. This study investigates the resistance patterns of bacteria isolated from blood, urine, and respiratory secretions of hospitalized patients to inform better treatment protocols.

Methods: A cross-sectional analysis was conducted involving 100 hospitalized patients in neurology departments. Samples from blood, urine, and respiratory secretions were collected and analyzed for bacterial culture and susceptibility testing using standard microbiological methods. Data on demographic and clinical variables were also collected.

Results: A total of 150 bacterial isolates were identified, with Escherichia coli (40%) and Klebsiella pneumoniae (30%) being the most prevalent. Notably, 85% of E. coli isolates exhibited resistance to ampicillin, while 60% showed resistance to ciprofloxacin. Blood isolates displayed the highest resistance rates, emphasizing the need for targeted treatment in this vulnerable population.

Conclusion: The study highlights significant antibiotic resistance among bacterial isolates in neurology patients, necessitating enhanced antimicrobial stewardship and continuous monitoring of resistance patterns. These findings underscore the importance of tailoring antibiotic therapy based on local resistance profiles to improve patient outcomes.

Keywords

Antibiotic resistance

bacterial isolates

neurology

antimicrobial stewardship

Subjects