Covid
Parham Maroufi; Tala Pourlak
Abstract
Introduction: Determining pre-operative platelet levels and their potential correlation with intraoperative bleeding is an important area of investigation in tibia fracture surgery. Platelet parameters, including platelet count, MPV, PDW, and PCT, have shown promise as potential predictors of bleeding ...
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Introduction: Determining pre-operative platelet levels and their potential correlation with intraoperative bleeding is an important area of investigation in tibia fracture surgery. Platelet parameters, including platelet count, MPV, PDW, and PCT, have shown promise as potential predictors of bleeding tendencies during surgery. By considering these parameters and other relevant clinical factors, healthcare professionals can enhance surgical planning, optimize patient care, and improve outcomes in tibia fracture surgery.Material and Methods: Pre-operative platelet levels were determined by collecting a venous blood sample from each participant within 24 hours before surgery. The blood samples were collected using standard aseptic techniques and transferred to the hospital laboratory for analysis. Platelet counts were measured using an automated hematology analyzer, which provided accurate and reliable results. During tibia fracture surgery, the amount of bleeding was measured and recorded. The surgical team employed standard techniques for intraoperative blood loss measurement, including the use of suction devices and weighing surgical sponges.Results: The results revealed a significant positive correlation between platelet count and intraoperative bleeding (p < 0.05), indicating that higher platelet counts were associated with increased amounts of bleeding during tibia fracture surgery. However, no significant correlations were observed between MPV, PDW, PCT, and intraoperative bleeding (p > 0.05).Conclusion: this study provides evidence of a significant positive correlation between pre-operative platelet count and the amount of bleeding during tibia fracture surgery. Higher platelet counts were associated with increased amounts of bleeding, suggesting that platelet count may serve as a valuable predictor of bleeding tendencies in this surgical population.
Medicine
Amir Heydarian; Baharak Najafi Fakhraei Azar
Abstract
The management of acute abdomen referred in the emergency department is a complex and challenging task for healthcare professionals. Acute abdomen referred refers to abdominal pain that is perceived in a location distant from the actual underlying pathology. In the emergency department setting, the primary ...
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The management of acute abdomen referred in the emergency department is a complex and challenging task for healthcare professionals. Acute abdomen referred refers to abdominal pain that is perceived in a location distant from the actual underlying pathology. In the emergency department setting, the primary goals of management are to rapidly assess the patient, make an accurate diagnosis, and provide timely interventions to alleviate pain and prevent complications. In this conclusion, we will summarize the key aspects of managing acute abdomen referred in the emergency department. The management of acute abdomen referred in the emergency department begins with a thorough history and physical examination, which can provide valuable clues to the underlying cause. Prompt imaging studies, such as ultrasound, CT scans, or MRI, are often utilized to aid in the diagnosis. These imaging modalities provide detailed anatomical information and help identify the affected organs or structures contributing to the referred pain. Pharmacological interventions play a crucial role in the emergency management of acute abdomen referred. Analgesics, such as NSAIDs or opioids, are administered to relieve pain and provide comfort to the patient. Antibiotics may be initiated in cases where infection is suspected or confirmed. Proton pump inhibitors and antispasmodics are used to address specific causes of referred pain, such as peptic ulcers or functional gastrointestinal disorders. Surgical intervention may be necessary in cases where conservative management approaches fail or when a definitive diagnosis requires direct visualization and tissue sampling. Emergency surgical procedures such as appendectomy, cholecystectomy, or salpingectomy are performed to address specific underlying causes of acute abdomen referred. In the emergency department, timely decision-making and effective communication among healthcare professionals are crucial for the optimal management of acute abdomen referred. Multidisciplinary collaboration, involving emergency physicians, surgeons, radiologists, and other specialists, ensures a comprehensive approach to diagnosis and management.
Medicine
Mehrnoosh Rassam; Abbasali Dehghani; Ramin Azhough
Abstract
Introduction: In the subsequent sections of this article, we will delve into the specific methodologies employed in video-assisted pilonidal sinus surgery with minimally invasive hook circulators, review existing literature on postoperative pain outcomes, and discuss the implications of these findings ...
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Introduction: In the subsequent sections of this article, we will delve into the specific methodologies employed in video-assisted pilonidal sinus surgery with minimally invasive hook circulators, review existing literature on postoperative pain outcomes, and discuss the implications of these findings for the future of pilonidal sinus disease management.Material and Methods: Postoperative pain was assessed using a validated pain scale, such as the Visual Analog Scale (VAS) or Numerical Rating Scale (NRS). Pain scores were recorded at predefined intervals post-surgery, including immediately upon awakening, at discharge, and during follow-up visits on days 1, 3, 7, and 14.Results: Postoperative pain was assessed using the Visual Analog Scale (VAS) at various time points: immediately upon awakening, at discharge, and during follow-up visits on days 1, 3, 7, and 14. The pain scores were consistently low across all time points, indicating minimal postoperative pain. This trend suggests effective pain management associated with the use of minimally invasive hook circulators.Conclusion: the study's results support the favorable impact of minimally invasive hook circulators on postoperative pain outcomes in pilonidal sinus surgery. The reduced pain scores, minimal analgesic requirements, and improved recovery trajectories underscore the potential benefits of incorporating these techniques into clinical practice.
Health
Melika Shojaei
Abstract
This study has systematically investigated the effect and safety of alendronate on bone density in patients with chronic kidney disease. In this study, by reviewing more than 75 articles and by searching keywords such as: Safety of alendronate, bone density, chronic kidney disease, the issue has been ...
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This study has systematically investigated the effect and safety of alendronate on bone density in patients with chronic kidney disease. In this study, by reviewing more than 75 articles and by searching keywords such as: Safety of alendronate, bone density, chronic kidney disease, the issue has been investigated. Alendronate tablet with the English name Alendronate is one of the well-known drugs for patients with osteoporosis and others who are exposed to this disease. Most of its users are postmenopausal women and people who have been treated with corticosteroids for any reason. The results of the present study showed that this drug slows down the activity of cells that play a role in bone decomposition. Therefore, its consumption can be effective in strengthening bones and reducing the risk of fractures, especially in the elderly. This drug does not help reduce the pain caused by a broken bone, and patients should use other treatment methods to relieve their pain. It is not known whether NSAIDs increase the need for dialysis. Therefore, the available data do not confirm the safety of NSAIDs in patients undergoing surgery. More studies involving patients with other health problems are needed. Patients with chronic kidney disease (CKD) are more at risk of developing osteoporosis (bone weakening), which can often lead to bone fractures. The results of this study showed that this drug may cause ulcers and erosions in the esophagus (the tube that connects the throat to the stomach), which can sometimes be severe. Symptoms of this condition may include heartburn, difficulty swallowing or pain when swallowing, chest pain, vomiting blood, or black or bloody stools. Tell your doctor immediately if you have these symptoms.
Health
Melika Shojaei
Abstract
The present study systematically investigated the relationship between sex hormones and leptin in men. In this study, 70 articles were reviewed and the subject was investigated by searching the words "Leptin", "Patients undergoing surgery" and "Sex hormone". Leptin is a hormone derived from adipose tissue ...
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The present study systematically investigated the relationship between sex hormones and leptin in men. In this study, 70 articles were reviewed and the subject was investigated by searching the words "Leptin", "Patients undergoing surgery" and "Sex hormone". Leptin is a hormone derived from adipose tissue that plays a major role in the pathogenesis of obesity. Hyperinsulinemia and insulin resistance are among the complications of obesity. Hyperinsulinemia is one of the factors that seems to affect the leptin hormone level. Few studies have investigated the relationship between leptin and insulin resistance in obesity in children and adolescents. Leptin is made by fat cells, and for this reason, with the presence of these cells and the increase in messaging, when the leptin hormone increases, the message of satiety is sent to the brain; As a result, the person reduces his food consumption. However, sometimes due to the excessive increase of leptin caused by eating sweet and fructose-containing foods, the brain loses its sensitivity to the leptin hormone and does not receive the message of satiety. For this reason, leptin hormone and obesity are related to each other; But their relationship cannot be considered linearly. In many cases, after testing the obesity hormone leptin, the doctor concludes that a person who is overweight has developed a strong resistance to the hormone leptin; Therefore, by prescribing some solutions, such as reducing the amount of fruit consumption, increasing the regularity and hours of rest and sleep, reducing the consumption of sugary foods and changing the diet, as well as consuming enough water, it tries to increase the sensitivity of the brain to the leptin hormone. The results of the recent study showed that the relationship between leptin and insulin resistance was weak and after controlling for body mass index, the relationship disappeared.
Medicine
Ali Reza Lotfi; Abbasali Dehghani
Abstract
Introduction: Pain intensity represents an important but understudied aspect of sinonasal mucormycosis surgery. Understanding the relationship between pain intensity and mortality is crucial for optimizing pain management strategies and improving patient outcomes.Material and Methods: Data collection ...
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Introduction: Pain intensity represents an important but understudied aspect of sinonasal mucormycosis surgery. Understanding the relationship between pain intensity and mortality is crucial for optimizing pain management strategies and improving patient outcomes.Material and Methods: Data collection was conducted by reviewing electronic medical records and surgical databases to extract relevant information on patient demographics, clinical characteristics, surgical procedures, pain intensity scores, and mortality outcomes. Pain intensity scores were assessed using validated pain assessment tools such as the Numerical Rating Scale (NRS) or Visual Analog Scale (VAS).Results: The results of the multivariable Cox proportional hazards regression analysis revealed that pain intensity was significantly associated with mortality (HR: 1.82, 95% CI: 1.45 - 2.28, p < 0.001). After adjusting for age, comorbidities, and surgical procedures, each unit increase in pain intensity was associated with a 1.82-fold increase in the hazard of mortalityConclusion: Our study highlights the significant association between pain intensity and mortality following sinonasal mucormycosis surgery. Effective pain management plays a crucial role in optimizing outcomes for patients undergoing surgical treatment for mucormycosis, and efforts to improve pain control should be integrated into perioperative care protocols.
Health
Franki Janlio
Abstract
Repetition and type of oral hygiene should be done based on oral cavity examination instead of routine. A soft, small toothbrush with a neutral pH moistened with water is more effective than scrubs or sticky foams. Hydrogen peroxide diluted in a 20% solution in a ratio of 1 to 4 diluted with water or ...
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Repetition and type of oral hygiene should be done based on oral cavity examination instead of routine. A soft, small toothbrush with a neutral pH moistened with water is more effective than scrubs or sticky foams. Hydrogen peroxide diluted in a 20% solution in a ratio of 1 to 4 diluted with water or sodium bicarbonate (one-half teaspoon per 500 cc) of water can be used to remove debris and dissolve thick mucus. If there are signs of infection such as stomatitis or generitis, antimicrobial mouthwashes or toothpaste such as (Chalrhexidine gluconate 1%) can be used, but the best way to prevent infection is to clean plaque. To prevent dry lips, they should be lubricated with Vaseline or kg gel. Neutral mouthwash solution that does not cause dry mouth, as it may be very easy to use by the patient, but has not been shown to have an effect on maintaining mucosal cohesion. Limited use of glycerin and lemon water-absorbing mouthwash 2-3 times a day may help stimulate saliva secretion. Artificial saliva spray can be used if the mouth is very dry and the patient's fluid intake is limited or they have difficulty swallowing. Dentures should be removed at night, cleaned and soaked in water. Being hydrated will help relieve dry mouth.
Bio-Chemistry
Mohammad Parsa
Abstract
A fuel cell is a device that converts the chemical energy of the fuel directly into electrical energy. Hydrogen gas is used as an ideal fuel in a fuel cell due to its high reactivity, abundance and lack of environmental pollution. In order to produce energy with optimal efficiency, the fuel cell series ...
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A fuel cell is a device that converts the chemical energy of the fuel directly into electrical energy. Hydrogen gas is used as an ideal fuel in a fuel cell due to its high reactivity, abundance and lack of environmental pollution. In order to produce energy with optimal efficiency, the fuel cell series requires additional equipment called the fuel cell system, which optimal performance conditions for the fuel cell include fuel purity, the amount of air and fuel entering the fuel cell series, gas humidity and water management, temperature control and finally control the gas pressure in the fuel cell system and series. According to the type of fuel cell and its application, these systems are simple or complex, for example, in power plant fuel cells, the fuel converter part that converts fossil fuels, biomass into pure hydrogen, is the main and complex part of the fuel system. In automotive applications, the refueling system can take the following two forms depending on the type of fuel infrastructure: If hydrogen is produced at the refueling station, the vehicle fuel storage system can use different methods such as hydrogen storage in pressure tanks, Use of nanotubes, use of metal hydride absorbers, use of chemical hydrides. In case of hydrogen production in the car, the fuel converter (especially the gasoline and methanol converter) that can be installed on the car is the main and complex part of the fuel system in the car.
Bio-Chemistry
Mohammad Parsa
Abstract
In the present study, hydrogen production and storage systems have been investigated. Underground hydrogen storage is suitable for providing high voltage network energy storage for intermittent and periodic energy sources such as wind power, in addition to providing fuel for transportation, especially ...
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In the present study, hydrogen production and storage systems have been investigated. Underground hydrogen storage is suitable for providing high voltage network energy storage for intermittent and periodic energy sources such as wind power, in addition to providing fuel for transportation, especially for use in ships and airplanes. Most of the research conducted in the field of hydrogen storage emphasizes the storage and maintenance of hydrogen as a dense, light and compact energy carrier for mobile applications. Liquid hydrogen requires cryogenic storage and boils at -252,882°C or -423,188°F. Therefore, its water content is subject to a large reduction and loss of energy. Tanks should also be installed well in order to prevent excessive boiling, but adding insulation or non-conductor will result in higher costs. Liquid hydrogen has a lower energy density in terms of volume and capacity compared to hydrocarbon fuel. Compressed and condensed hydrogen is stored in a completely different way. Hydrogen gas has a good energy density in terms of weight, but its energy density is low in terms of volume and capacity compared to hydrocarbons. Therefore, it requires a larger tank for storage. A large hydrogen tank will be heavier than a small hydrocarbon tank used to store the same amount of energy, all other factors remaining equal. Increasing gas pressure improves energy density in terms of volume and capacity, which favors smaller, though not lighter, tanks.
Medicine
Mahla Effati; Majid Montazer Bavil Olyaee
Abstract
Introduction: Over the past few decades, advances in surgical techniques and perioperative management have led to improvements in the prognosis of thoracic esophageal perforation. However, the optimal treatment approach remains controversial, with various surgical techniques available and differing outcomes ...
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Introduction: Over the past few decades, advances in surgical techniques and perioperative management have led to improvements in the prognosis of thoracic esophageal perforation. However, the optimal treatment approach remains controversial, with various surgical techniques available and differing outcomes reported in the literatureMaterial and Methods: Data collection was conducted by reviewing electronic medical records, surgical databases, and pathology reports to extract relevant information on patient demographics, clinical characteristics, preoperative evaluations, surgical techniques, intraoperative findings, postoperative outcomes, and long-term prognosis. Data on surgical techniques utilized in the treatment of thoracic esophageal perforation were meticulously documented.Results: Surgical management was performed in all 80 patients, with various surgical techniques employed based on the extent and severity of esophageal injury. Primary repair of the esophageal perforation was performed in 45 patients (56.3%), esophageal diversion with cervical esophagostomy in 25 patients (31.3%), and esophagectomy with reconstruction in 10 patients (12.5%). The choice of surgical technique was guided by the surgeon's preference, extent of esophageal injury, and presence of associated comorbidities.Conclusion: Our study provides valuable insights into the seven-year prognosis and outcomes of surgical techniques used in the treatment of thoracic esophageal perforation. Despite the challenges associated with surgical management, including perioperative complications and mortality, surgical intervention remains essential for improving patient outcomes and reducing long-term morbidity.
