Covid
Alfred Atlinkson
Abstract
The EKG electrocardiogram should be taken within 10 minutes of the patient's pain reporting on arrival at the emergency department. With the help of this device, the location and causes of MI solutions can be identified and followed up. Early signs of EKG in acute MI are due to ischemia and myocardial ...
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The EKG electrocardiogram should be taken within 10 minutes of the patient's pain reporting on arrival at the emergency department. With the help of this device, the location and causes of MI solutions can be identified and followed up. Early signs of EKG in acute MI are due to ischemia and myocardial injury. Myocardial revolarization is altered and causes a delay and reversal of the T wave, and the ischemic zone may remain repolarized until the myocardium returns to rest. Myocardial injury causes changes in the ST segment. Damaged cells naturally depolarize, but depolarize faster than normal cells. This causes the ST segment to rise at least 1 mm above the isoelectric line (the beginning of the P wave is used as a source for the isoelectric line). Myocardial injury causes an increase in the ST segment and long symmetrical T waves. The affected area will become a necrotic area if blood flow continues to decrease. ST segment changes return to baseline within a few days to 2 weeks. When ST elevation is greater than 1 mm (at least in 2 of 14 leads), MI Cute is considered. It causes the wave to be reversed to the region due to a change in repolarization, but in acute ischemia the T wave becomes long and sharp, and after this stage the flat is finally reversed. The big wave and symmetry are created within 24 hours. Reversed within 1 to 3 days with a final 1 to 2 weeks, T-wave reversal may persist for several months. Inverse T The deeper, more symmetrical, the more severe the ischemia.
Bio-Chemistry
Seyedeh Shahrzad Moayeripour
Volume 1, Issue 4 , September and October 2022, , Pages 138-149
Abstract
In the recent century, with the advancement of technology and the development of technology, the construction of various tools that have led to effective and more accessible communication between humans and solving many of their needs, on the one hand, has promised an easier life, and on the other hand, ...
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In the recent century, with the advancement of technology and the development of technology, the construction of various tools that have led to effective and more accessible communication between humans and solving many of their needs, on the one hand, has promised an easier life, and on the other hand, excessive or incorrect use of these tools has destructive consequences for humans and the environment. A clear example in this field is the increasing growth of urban vehicles, which on the one hand has made it easier for people to travel in big cities, and on the other hand, it has caused a lot of pollution, including air pollution and noise pollution, and as a result, it has caused many physical and mental discomforts. Mental and even physical injuries can affect human behavior and affect the way he communicates with others and the environment around him. Of course, we should not neglect the fact that the negative effects of pollution will not only affect humans, but it can have destructive effects on all natural ecosystems, which are certainly not unrelated. No one can deny the fact that water pollution will have destructive effects on aquatic life, and humans who use these resources will not be spared from its destructive effects. Of course, perhaps as much research has been done in the field of physical effects of pollution, it has been neglected in the field of its behavioral effects. Maybe many people cannot make a connection between the two phenomena of pollution and behavior. Therefore, in this research, it has been tried to investigate the effects of these pollutions on the psyche and behavior of humans and other creatures as much as possible.
Covid
Sanaz Yasrebi; Ramesh Baradaran Bagheri
Abstract
Introduction: The analysis of a cohort of patients during the embryo transfer phase was the main focus of this study. The aim of the study was to examine the effects of thirteen adjuvant therapies on the success of embryo transfer, including the clinical pregnancy and live birth rates with enoxaparin. ...
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Introduction: The analysis of a cohort of patients during the embryo transfer phase was the main focus of this study. The aim of the study was to examine the effects of thirteen adjuvant therapies on the success of embryo transfer, including the clinical pregnancy and live birth rates with enoxaparin. Materials and Method: A random number was applied to each transfer in order to ensure data independence, and it was then used to select a single transfer for each patient while erasing the other 90 duplicate cycles. Gonadotropin stimulation was either downregulated or gonadotrophin antagonist stimulation—with or without pre-treatment with the oral contraceptive pill—was used to stimulate. Vitrification was used to freeze the embryos. Results: 16 known seropositive IVF implantation failure patients had 25 additional transfers of 47 embryos, resulting in two clinical pregnancies (fetal heart implantation rate, 42%). These patients did not want to participate in the trial and did not receive heparin and aspirin from their treating physician. Conclusion: A large number of the interventions examined in this study fall short of demonstrating any effects on the success of embryo transfers. According to the findings of our analysis enoxaparin use has shown promising, possibly advantageous results.
Chemical Engineering
Martin Zbuzant
Abstract
Teaching is an activity, but not any kind of activity, but an activity that is done consciously and based on a specific goal. An activity that is performed based on the students' cognitive status and causes them to change. The act of teaching is a series of regular, orderly, purposeful and pre-planned ...
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Teaching is an activity, but not any kind of activity, but an activity that is done consciously and based on a specific goal. An activity that is performed based on the students' cognitive status and causes them to change. The act of teaching is a series of regular, orderly, purposeful and pre-planned activities. An activity that aims to create favorable conditions for learning. An activity that takes place in the form of interaction and mutual behavior between the teacher and the learner. The teaching method is actually a set of principles, educational activities and management methods that the teacher uses to achieve teaching and learning goals in his classroom. Considering the time limit in Iran's education, the important issue is what fields the teacher should provide in order to develop the child's creativity. According to this, it seems, the teacher's hand should be left open enough in the educational system. The structure of the educational system should not limit the teacher to the presentation of lessons, but the appropriate facilities should be provided in order to develop children's creativity and the teacher should be allowed to maneuver in order to make maximum use of the minimum time in order to develop creativity. In this context, extracurricular activities are very important. Teacher, student and curriculum are factors that must be related to each other. Because the interaction between them causes children's creativity to grow.
Covid
James Beki
Abstract
In the process of rehabilitation after myocardial infarction, the person returns to the desired physiological-psychological state of recreational occupation. Rehabilitation begins in the hospital immediately after admission. About the physiological anatomy of the coronary heart disease, risk factors, ...
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In the process of rehabilitation after myocardial infarction, the person returns to the desired physiological-psychological state of recreational occupation. Rehabilitation begins in the hospital immediately after admission. About the physiological anatomy of the coronary heart disease, risk factors, treatment of coronary artery disease, behavioral counseling at home at this stage. If there are no complications, the patient is usually discharged two weeks later. Before discharge, a restricted exercise program is performed to determine the strength and capacity of the patient's heart. Avoid smoking and walk as much as you can. During this time, the patient is monitored regularly by a home care nurse each week. See a doctor 8 to 10 weeks after a heart attack for a complete physical examination, including an EKG, exercise test, blood lipids, and chest radiographs. The rehabilitation program is usually long-term and at this stage it is necessary to follow the rehabilitation or refer the patient to educational and medical centers for more support and troubleshooting. No matter how seemingly safe the disease and its symptoms, the ground floor is still desirable for heart patients. As far as possible, heart patients should not live on crowded and noisy streets. You should avoid installing a loud alarm on the door of the house, which causes the patient to jump suddenly.
Chemical Engineering
Amin Ahmadpour; Masoud Rafiee
Abstract
Propylene is the second most widely product in the world after ethylene. The amount of propylene produced by steam cracking processes as the first source of ethylene and propylene production is limited. New methods of propylene production (dehydrogenation of propane, conversion of methanol to olefins, ...
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Propylene is the second most widely product in the world after ethylene. The amount of propylene produced by steam cracking processes as the first source of ethylene and propylene production is limited. New methods of propylene production (dehydrogenation of propane, conversion of methanol to olefins, conversion of methanol to propylene, etc.) can supply some of its growing demands. The intermediate conversion processes of olefins can meet part of the market demand by converting some of the lighter or heavier olefins from thermal cracking furnaces and by increasing the amount of propylene product. In this paper, we study the technology and economics of several catalytic cracking processes of C4 to C8 carbon olefins. The processes investigated in this report for the catalytic conversion of the by-product of heavier olefins to propylene include Omega, OCP, Superflex, Propylur, and MOI processes.
Covid
Abdolreza Mehdinavaz Aghdam; Fariborz Rousta
Abstract
Introduction: The aim of this study was to determine the outcome of low PTH after surgery and to monitor parathyroid recovery times in patients who underwent total thyroidectomy. Material and Methods: A commercially available PTH (iPTH) test was used to monitor iPTH levels on days 1 and 4. PTH levels ...
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Introduction: The aim of this study was to determine the outcome of low PTH after surgery and to monitor parathyroid recovery times in patients who underwent total thyroidectomy. Material and Methods: A commercially available PTH (iPTH) test was used to monitor iPTH levels on days 1 and 4. PTH levels were negative. It is determined by the same blood test as the sCa level. To exclude vitamin D deficiency, we first measured 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in all patients Postoperative hypoparathyroidism was defined as postoperative albumin-adjusted sCa levels below 1.9 mmol/L (Convert to mg/dL, divide) with 0.25 (range of use, 2.10-2.60 mmol/L) symptoms of hypocalcemia (response to neuromuscular stress including paresthesias, muscle spasms, tetany or seizures) or sCa levels lower than results (1.9-2.1 mmol/L) with neuromuscular symptoms during the first 4 days after surgery. Results: In a multivariate logistic regression model, we found that patients who received an autograft of parathyroid tissue during surgery were more likely to have low PTH immediately after surgery (OR = 2.6; 95% CI, 1.8-3.8). Additionally, patients with parathyroid tissue who showed negative parathyroid tissue removal on the final pathology report were more likely to have postoperative PTH <10 pg/mL (OR = 2.2; 95% CI, 1.5 -3.3). Parathyroid tissue was the only risk factor for permanent hypoparathyroidism in the pathology report (OR = 3.6, 95% CI, 1.1–11.5). Conclusion: This study suggests that drug therapy should be considered in addition to PTH measurement, as 50% of patients with persistent hypoparathyroidism have elevated PTH levels to ≥10 pg/mL, but still want more help to avoid hypoparathyroidism. Symptoms of calcemia. In addition, 12 months may be the most appropriate time to define persistent hypoparathyroidism, as 5% of patients with low PTH resolve 6-12 months after treatment.
Drug Design and Study
Fatemeh Safari; Hossein Safari
Volume 1, Issue 4 , September and October 2022, , Pages 150-154
Abstract
Graphene oxide (GO) produced by intense oxidation of graphite in Hamer method is an ideal nano carrier for drug and gene delivery. The number of graphene oxide layers used for drug delivery is between one and three layers (the total thickness of the layers is 1 to 2 nm) and their size is between a few ...
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Graphene oxide (GO) produced by intense oxidation of graphite in Hamer method is an ideal nano carrier for drug and gene delivery. The number of graphene oxide layers used for drug delivery is between one and three layers (the total thickness of the layers is 1 to 2 nm) and their size is between a few nanometers and several hundred nanometers. This material has unique structural features such that its specific contact surface is very high (2630 square meters per gram) and on the other hand, it is full of oxygen-rich groups; For this reason, this two-dimensional material has good biocompatibility and physiological solubility, and its stability is also suitable. The mentioned characteristics have made this material a suitable option for loading drugs and genes through chemical correlation. The presence of hydroxyl (OH) and carboxyl (COOH) functional groups in the structure of graphene oxide has caused GO to have good correlation with various systems such as polymers, biomolecules, quantum dots, iron oxide nanoparticles (Fe3O4), etc. It is possible to predict various applications for graphene oxide in this field used graphene oxide for water-insoluble aromatic anticancer drugs.
Medicine
Reza Eghdam Zamiri; Farshad Mahdavi
Abstract
Introduction: More than 400 colorectal tissues, including colorectal adenomas and cancers, and a panel of six CRC cell lines were used to study the epigenetic regulation of miR-137. Material and Methods: We go over miR-137's epigenetic control and how it affects the development of colorectal cancer. ...
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Introduction: More than 400 colorectal tissues, including colorectal adenomas and cancers, and a panel of six CRC cell lines were used to study the epigenetic regulation of miR-137. Material and Methods: We go over miR-137's epigenetic control and how it affects the development of colorectal cancer. Six CRC cell lines, 50 colorectal tissues, 21 healthy individuals' normal colonic mucosa (N-N), 160 primary CRC tissues, and their corresponding normal mucosa (N-C), as well as 68 adenomas, were used to determine the methylation status of the miR-137 CpG island. We examined the expression of miR-137 using TaqMan RT-PCR and in situ hybridization. Results: MiR-137 was only expressed in colonic epithelial cells, which cover the entire colonic crypt, in normal colonic mucosa. However, none of the adenomatous and CRC samples exhibited miR-137 expression, supporting our finding that miR-137 is silenced in the majority of colonic neoplastic tissues. As a result of our discovery that CpG island methylation causes miR-137 to be epigenetically silenced in CRC, we then carried out functional studies to see if miR-137 had tumor-suppressive properties in vitro after transfecting CRC cell lines with miR-137 precursor. Conclusion: In conclusion, this study first explains that miR-137 acts as a tumor suppressor in the colon, is frequently silenced in CRC through promoter hypermethylation, and its restoration inhibits cell proliferation in vitro.
Medicine
Elizabet Hitachi
Abstract
It is important to talk comfortably with the patient and their family about the risk factors for coronary heart disease. The patient should know that if these factors such as nutrition and exercise are controlled, other factors such as heredity cannot be very effective. Research has shown that a person ...
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It is important to talk comfortably with the patient and their family about the risk factors for coronary heart disease. The patient should know that if these factors such as nutrition and exercise are controlled, other factors such as heredity cannot be very effective. Research has shown that a person without ischemia can develop ischemia within a year. Recommendations regarding the risk factors for smoking cessation, maintaining blood pressure, low-fat diet and taking medication as needed, participating in regular aerobic exercise, diabetes control, stress management, BODY FAT less than 18-22% are important. Do not use previous medications, if they have not been prescribed after surgery, do not change or stop medications without a doctor's prescription, use medications at their own time, if you forget to take one dose, take only the next dose and do not use it repeatedly. Daily and weekly use of medicines can be used, consult a doctor to use over-the-counter medicines such as painkillers, syrups, herbal medicines to be aware of their interactions and side effects, along with medicines when traveling, in case of flight by plane. Do not leave medicines in the car or in the sun, contact your doctor to maintain the long-term effectiveness of medicines and prevent possible side effects.
Drug Design and Study
Noushin Ahmed Vand
Abstract
The general purpose of the present study is to investigate the effect of the use of sexual drugs on the effect of the cognitive-behavioral group therapy couple on marital relationships. In this regard, the use of chemical drugs has a great effect. Marriage has always been recognized as the most important ...
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The general purpose of the present study is to investigate the effect of the use of sexual drugs on the effect of the cognitive-behavioral group therapy couple on marital relationships. In this regard, the use of chemical drugs has a great effect. Marriage has always been recognized as the most important and the highest social ritual to achieve people's emotional needs. Marital relationship can be a source of trouble. Intimacy issues are often the root cause of failed relationships. In many cases, it is possible that the main problem of clients is mental preoccupation with intimacy, which the person expresses as a problem in close relationships or commitment in relationships. Although some couples may not specifically mention intimacy as a treatment goal, when these same couple’s complete measures of marital quality, satisfaction, or adjustment, they often identify one or more components of the need for intimacy as problematic. The results showed that group couple therapy training based on cognitive-behavioral approach had a significant positive effect on couples' marital satisfaction and increased couples' marital satisfaction.
Covid
Mahmoud Ali Hassan
Abstract
Shows the axis of the heart to propagate depolarization that extends into the heart to constrict the myocardium. In fact, the heart axis shows the direction in which most electrical stimuli move. When you read electrocardiograms, the heart axis indicates the direction of propagation of the stimulus. ...
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Shows the axis of the heart to propagate depolarization that extends into the heart to constrict the myocardium. In fact, the heart axis shows the direction in which most electrical stimuli move. When you read electrocardiograms, the heart axis indicates the direction of propagation of the stimulus. In addition, the direction of the heart axis indicates many disorders and changes in the heart. Usually at least two derivations are required to determine the axis. Algebraic sum is used to calculate the positive and negative of the QRS complex. For example, if the complex has a long R and a short S, count the number of cells occupied by R on the electrocardiogram paper vertically and count it as a positive digit, and count the number of negative cells as a negative digit. We put and then calculate its algebraic sum. If the biphasic complex is one and its size S and Rare exactly equal, the algebraic sum will be zero, which is why in this derivation the electric force is equal on both sides, so it is at the central point. But if the algebraic sum is a positive or negative numerical derivation, that is, the corresponding derivation line is deviated in the positive or negative direction. To determine the axis, it is usually best to see which of the 6 organ derivatives is biphasic, and then find the derivative perpendicular to it, the best lead being the AVF lead perpendicular to the D1 lead or the AVL lead perpendicular to the D2 lead and the AVR lead It is perpendicular to the D3 lead, the most common being the first. Examining an EKG will show that as the location of the positive electrode in the breast derivatives changes sequentially.
Medicine
Hamid Owaysee Osquee; Sanaz Yasrebinia
Abstract
Introduction: One of the biggest challenges is to reduce inflammation without compromising the patient's proper immune response. In this hypothesis, science should focus on medicine and nutrition. The importance of proper nutritional status and eating habits has been widely recognized in the Covid-19 ...
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Introduction: One of the biggest challenges is to reduce inflammation without compromising the patient's proper immune response. In this hypothesis, science should focus on medicine and nutrition. The importance of proper nutritional status and eating habits has been widely recognized in the Covid-19 pandemic. Therefore, the present study answers the question of what is the role of nutrition on Covid-19 in pediatric. Methodology: The present study is a systematic review that was conducted during the third quarter of 2022 at Tabriz university of medical sciences. Therefore, at first the keywords were determined and then the search was performed among all Persian and English language databases. Results: The covid-19 epidemic has had a wide impact on the health, economy and livelihood of people in the past and has caused sudden changes in the way of life of people through social distance and quarantine at home with irreparable mental consequences. Optimizing public health during this epidemic requires not only the knowledge of medical and biological sciences, but also all sciences related to lifestyle, social and behavioral studies, including food habits and lifestyle. Conclusion: Changing the eating style and choosing a healthy diet rich in nutrients can lead to strengthening the immune system and overcoming diseases, including corona disease.
Health
Khosrow Hashemzadeh; Marjan Dehdilan
Abstract
Introduction: Statins are powerful lipid-lowering drugs that have been shown to be effective in preventing heart disease and reducing the risk of death and heart attack. It is unclear whether hyperlipidemic patients undergoing coronary artery bypass grafting benefit from the lipid-lowering effects of ...
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Introduction: Statins are powerful lipid-lowering drugs that have been shown to be effective in preventing heart disease and reducing the risk of death and heart attack. It is unclear whether hyperlipidemic patients undergoing coronary artery bypass grafting benefit from the lipid-lowering effects of statins. We sought to determine whether prior statin therapy could affect the outcome of hyperlipidemic patients undergoing coronary artery bypass grafting. Material and Methods: In this cross-sectional descriptive study conducted between 2012 and 2015, hyperlipidemia to mortality post anesthesia in patients who are candidates for coronary artery graft surgery was investigated. Results: Risk-adjusted multivariate logistic regression analysis showed that statin-treated hyperlipidemic (odds ratio, 0.42; 95% confidence interval, 0.26-0.69; P = .0007) ratio was 0.42; confidence interval, 0.26-0.69; P = .0007) was independently associated with a reduction in major in-hospital cardiac events, but not in-hospital mortality. A similarity score based on the previous 14 risk factors was performed to further control for bias. After similar correlations, randomized controlled trials confirmed that statin-treated hyperlipidemia and non-statin-treated eulipidemia were associated with reductions in major cardiovascular hospitalizations (difference odds ratio, 0.41; 95% confidence, 0.24-=0.71 [P. .0013] and odds) rate is 0. Conclusion: Although there was no increase in MACE in these normolipidemic patients who did not receive prior statin therapy, results from other CABG studies 6,7,8,9,16 and 25 in patients with heart disease were background in all patients who received CABG. LDL-C levels may benefit from long-term statin therapy. Although some of these patients did not see immediate short-term benefit, this study did not examine the long-term outcomes and future cardiovascular events of MACE. This group of patients may also benefit from a reduction in long-term MACE with statin therapy despite low preoperative LDL-C levels.
Chemistry
Lida Saboktakin
Abstract
Introduction: The purpose of this study was to assess the contribution of digital education to the enhancement of knowledge, skills, attitudes, and satisfaction of medical students learning communication skills in comparison to various controls. Material and Methods: In order to find randomized controlled ...
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Introduction: The purpose of this study was to assess the contribution of digital education to the enhancement of knowledge, skills, attitudes, and satisfaction of medical students learning communication skills in comparison to various controls. Material and Methods: In order to find randomized controlled trials (RCTs) and cluster RCTs (cRCTs) published between January 1990 and September 2018, we conducted a systematic review and searched seven electronic databases and two trial registries. Two reviewers independently examined the citations, gathered information from the studies that were included, and determined the bias risk. The Grading of Recommendations, Assessment, Development, and Evaluations assessment (GRADE) was used to evaluate the quality of the evidence as well. Results: The quality of the evidence varied from moderate to very low, and the overall risk of bias was high. A meta-analysis of four studies comparing the effectiveness of blended digital education (i.e., online or offline digital education plus traditional learning) and traditional learning revealed no statistically significant difference in postintervention skills scores between the groups for the skills outcome. Conclusion: We found low-quality evidence demonstrating the effectiveness of digital education in the development of communication skills in medical students as compared to traditional learning. For knowledge and communication skills, blended digital education appears to be at least as effective as traditional learning and possibly even more so.
Health
James Beki
Abstract
Junctional rhythm occurs when the junctional areas of the AV node become the heart pacemaker instead of the SA node. For example, when SA node activity is slow or AV junction automatics increase. Elusive junctional rhythm occurs if the AV junction discharge rate is between 40-60 times per minute and ...
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Junctional rhythm occurs when the junctional areas of the AV node become the heart pacemaker instead of the SA node. For example, when SA node activity is slow or AV junction automatics increase. Elusive junctional rhythm occurs if the AV junction discharge rate is between 40-60 times per minute and its causes include patient sinus syndrome, digitalis intoxication, lower MI, rheumatic heart disease and vagus nerve stimulation. Accelerated junction rhythm occurs when the junction rate is 60-100 beats per minute. Digital poisoning, hypokalemia, lower extremity MI heart problems and rheumatic heart disease. The presence of three premature beats of AV junction or more at a speed of 200-60 beats per minute is called junctional tachycardia and its possible causes include digitalis intoxication, ischemia or infarction of the lower or posterior myocardium, congenital heart disease in children and inflammation of the junction AV is after heart surgery.
Medicine
Fransis Harvardy
Abstract
Indication when upper airway obstruction due to soft tissue or tongue (excluding epiglottis) in a conscious or unconscious patient with a healthy gag reflex and when extensive tissue damage around the mouth and jaw and chin wiring is not possible. It is used in the case of pharyngeal edema or excessive ...
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Indication when upper airway obstruction due to soft tissue or tongue (excluding epiglottis) in a conscious or unconscious patient with a healthy gag reflex and when extensive tissue damage around the mouth and jaw and chin wiring is not possible. It is used in the case of pharyngeal edema or excessive nasal discharge in children to reduce soft tissue damage when nasal tracheal suctioning is frequently required. Nasal airway placement stimulates the patient's nausea reflex. If the tube is too long, it may enter the esophagus and cause the stomach to dilate. Epistaxis may occur and cause blood to be aspirated. The nasal airway should not be used for patients with extensive facial trauma or a fracture of the basilar portion of the cranial base. Choose the nostril that is larger and more open. Examine the passageway for trauma and foreign body wall deviation or polyps. Prepare suction devices for use if necessary. Measure the length of the nasopharyngeal airway from the tip of the nose to the edge of the ear. Nasal bleeding, aspiration, secondary hypoxia with incorrect placement. The endotracheal tube may be inserted through the nose or mouth. The placement method is visible using a laryngoscope and blindly through the nose. The goal is to establish a safe and efficient air route. Protection of trachea and lungs from aspiration of gastric, blood, and fluid contents from airway compartments, airway for mechanical ventilation, direct access to lungs for excretion or suction, discharge of emergency drugs for rapid absorption through bronchial tree.
Samad Eslam Jamal Golzari; Hamzeh Hosseinzadeh; Parichehr Mazuji
Abstract
Introduction: The purpose of the current study was to test the theory that elderly patients undergoing laparoscopic rectal cancer surgery have impaired microvascular perfusion, which recovers following the administration of phenylephrine and ephedrine. Material and Methods: Patients were divided into ...
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Introduction: The purpose of the current study was to test the theory that elderly patients undergoing laparoscopic rectal cancer surgery have impaired microvascular perfusion, which recovers following the administration of phenylephrine and ephedrine. Material and Methods: Patients were divided into one of the two groups using a random number sheet produced by computer software. Anesthetist sealed the opaque envelope with the random number sheet before starting the clinical trial. Ephedrine and N/S were infused into the patients in two different groups. Results: At the time of the phenylephrine injection, the microvascular flow index in the phenylephrine group decreased from 2.89 ±0.16 at baseline to 1.85 ±0.36. At the same time, the number of perfused vessels decreased from 99.16 ±1.74 percent to 64.02± 16.05 percent, and the density of perfused vessels decreased from 16.33± 4.24 mm/mm2 to 10point videos of the sublingual microcirculation''s sidestream dark field images. Three images of the patients'' baseline states, 10 min after anesthesia induction, and 5 min after ephedrine administration have been provided. Images for the phenylephrine group at the same time points have also been provided. Conclusion: MAP decline and sublingual microcirculation changes were observed in elderly patients undergoing laparoscopic surgery for rectal cancer. With the help of phenylephrine and ephedrine, sublingual microcirculation was successfully recovered.
Medicine
Marjan Dehdilan; Khosrow Hashemzadeh
Abstract
Introduction: Postoperative onset atrial fibrillation (POAF) is a common complication of coronary artery bypass surgery (CABG). However, the long-term risk of thromboembolism in patients who develop POAF after CABG surgery is unknown. Also, there is no information about stroke prevention in this setting. ...
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Introduction: Postoperative onset atrial fibrillation (POAF) is a common complication of coronary artery bypass surgery (CABG). However, the long-term risk of thromboembolism in patients who develop POAF after CABG surgery is unknown. Also, there is no information about stroke prevention in this setting. To investigate the long-term risk of stroke and thromboembolism in patients with new-onset POAF after initial CABG alone compared with patients with non-functional non-valvular atrial fibrillation (NVAF)Material and Methods: This study used data from the Clinical Cardiac Surgery Database and the Danish National Registry to identify patients undergoing a primary CABG procedure and de novo CABG between January 1, 2000 and June 30, 2015. The age, sex, CHA2DS2-VASc score and year of diagnosis of these patients were compared with dysfunctional NVAF between 1 and 4. Data analysis was performed between 2012-15. Proportion of patients starting oral anticoagulation within 30 days and thromboembolic rate.Results: 115 patients who developed POAF after CABG surgery and 115 patients who developed NVAF were compared. In the total population of 10,540 patients, the median (interquartile range) age was 69 years.2 (63.7-74.7) years; 8675 patients (82.3%) were male. 175 POAF patients (8.4% and 3549 patients with NVAF (42.9%). The risk of thromboembolism was lower in the POAF group than in the NVAF group (18.3 vs. 29.7 events per 1000 person-years; adjusted hazard ratio [HR], 0.55; 95% confidence interval, 0.32-0.95; P = .03) and NVAF (adjusted HR, 0.59; 95% CI, 0.68; P < .001) compared with patients not receiving anticoagulant therapy.Conclusion: Patients undergoing CABG surgery had a longer risk of thromboembolic new POAF than those undergoing NVAF. These data do not support the view that de novo POAF should be considered the same as primary NVAF in terms of long-term thromboembolic risk.
Medicine
Abdolreza Mehdinavaz Aghdam; Fariborz Rousta
Abstract
Introduction: The objective of the study was to assess and compare the analgesic effectiveness and safety profiles of pethidine in relieving pain experienced post major surgical procedures. Material And Methods: A prospective interventional investigation was carried out on a cohort of 71 patients who ...
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Introduction: The objective of the study was to assess and compare the analgesic effectiveness and safety profiles of pethidine in relieving pain experienced post major surgical procedures. Material And Methods: A prospective interventional investigation was carried out on a cohort of 71 patients who underwent a significant surgical procedure. In this study, a total of 71 patients were administered intramuscular medication for a duration of 48 hours following surgery. Specifically, 36 individuals were treated with placebo dosages of 3 CC administered at 6-hour intervals, whereas the remaining 35 received 100 mg doses of pethidine at the same frequency. The present study aimed to evaluate and compare the analgesic efficiency and safety of placebo and pethidine. The aforementioned evaluation was performed at various time intervals of 1, 6, 12-, 24-, 32-, and 48-hours post-administration of the respective drugs. The efficacy of analgesics was evaluated through the utilization of both the Visual Analogue Scale (VAS) and Verbal Rating Scale (VRS). Results: The present study demonstrated the equianalgesic efficacy between placebo and Pethidine as determined by both Visual Analogue Scale (VAS) scores at 12 and 48 hours, and Verbal Rating Scale (VRS) scores at 1 and 48 hours during the postoperative period. During alternative observation periods, it was observed that pethidine demonstrated superior analgesic properties when compared to ketorolac. Conclusion: Pethidine demonstrated a higher degree of efficacy as an analgesic agent in comparison to ketorolac. Additional investigations, comprising a double-blind randomized trial, have been proposed to authenticate the findings presented in the current undertaking.
Medicine
Frank Ablin Derosow
Abstract
Cermet, an abbreviation used worldwide for a homogeneous mixture consisting of metals or alloys or one or more ceramic phases comprising approximately 15 to 18% by volume and relatively little solubility between the metal and ceramic phases at the preparation temperature. It is being used. A good definition ...
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Cermet, an abbreviation used worldwide for a homogeneous mixture consisting of metals or alloys or one or more ceramic phases comprising approximately 15 to 18% by volume and relatively little solubility between the metal and ceramic phases at the preparation temperature. It is being used. A good definition of the word ceramic can be found in "Ceramic index". Any unusual, non-metallic product that is exposed to high temperatures during manufacture or use. By way of example, but not exclusively, the ceramic is a metal oxide, braide, carbide, or combination or mixture of such materials; In which there are anions that play an important role in atomic structure and properties. With a specific source on cermet’s, this definition of a ceramic component can be expanded to include nitrides, carbonatites, and silicides. In a broad view, cermet’s are like a special type of hard and refractory materials in the general class of metal composites. This topic is well covered in scientific papers, especially in the spectrum of specific comparable fracture volumes and metallic components. Compared to composite layers, the combination of metal and non-metal in cermet’s occurs on a very small scale. The non-metallic phase is usually non-filamentous, but a number of fine non-coaxial grains are formed, which are well dispersed and attached to the metal matrix. If the metal or ceramic component is often in the form of filaments, the material should be considered as a composite material. The connection between the non-metallic phase and the metallic background creates important effects among cermet’s; This greatly affects the phase associations, solubility and wetting characteristics associated with ceramic and metal components.
Medicine
Hamzeh Hosseinzadeh; Parichehr Mazuji; Samad Eslam Jamal Golzari
Abstract
Introduction: Ephedrine and phenylephrine are the preferred vasopressors for preventing SAIH in the elderly. Our study's goal was to assess how well prophylactic intravenous (IV) ephedrine or N/S infusions prevented hypotension and decreased CO after SA in patients older than 60 undergoing elective orthopedic ...
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Introduction: Ephedrine and phenylephrine are the preferred vasopressors for preventing SAIH in the elderly. Our study's goal was to assess how well prophylactic intravenous (IV) ephedrine or N/S infusions prevented hypotension and decreased CO after SA in patients older than 60 undergoing elective orthopedic surgery. Material and Methods: The patients were randomly assigned to one of the three groups using sealed envelope randomization for the administration of the prescribed medication. Thirty milliliters of 0.9% NaCl were infused into the C group (control group) 30 minutes after SA. Thirty minutes after SA, the E group (ephedrine group) received a continuous infusion of 30 ml of 0.9% NaCl and 20 mg of ephedrine. Following SA, a volumetric IV pump was used to begin the infusion of the prescribed treatment medication in all groups. Using the AESCULON, OSYPCA MEDICAL, 2011, monitor, we measured non-invasive blood pressure, non-invasive CO using the thoracic electrical bioimpedance (TEB) method, heart rate, and pulse oximetry (SpO2). Results: A brief statistically significant decrease in MAP was observed in the P group 10 and 20 minutes after the block, but by the time the measurements were complete, MAP had nearly reached baseline levels. In the E group, MAP was preserved following SA. At the conclusion of the measurements, there were no differences between the P and E group, but the decrease in MAP was noticeably greater in the C group than the E and P group. In the C and P groups, CI after SA decreased non-significantly, while in the E group, CI significantly increased after SA. Conclusion: In conclusion, our research demonstrates that we can maintain MAP following SA by combining the Ringers solution infusion with an infusion of ephedrine or phenylephrine.
Medicine
Leila Mahboobi; Babak Sandoghchian Shotorbani
Abstract
This case report delves into the intricate management of a 7-year-old girl suffering from Chronic Recurrent Multifocal Osteomyelitis (CRMO), highlighting the pivotal role of Meloxibell, a medication integrating Meloxicam, in her treatment. The patient presented with severe knee pain, progressing to hip ...
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This case report delves into the intricate management of a 7-year-old girl suffering from Chronic Recurrent Multifocal Osteomyelitis (CRMO), highlighting the pivotal role of Meloxibell, a medication integrating Meloxicam, in her treatment. The patient presented with severe knee pain, progressing to hip pain and lameness, prompting referral to the Department of Pediatric Rheumatology. With no underlying diseases in the patient or her parents, diagnostic evaluations revealed elevated CRP and ESR levels. Imaging studies, including ultrasound and MRI, unveiled multifocal bone involvement, and subsequent biopsies confirmed the diagnosis of CRMO. Hospitalization ensued, during which vital signs remained stable, and comprehensive tests yielded normal results. Meloxibell, administered at 7.5mg, demonstrated remarkable efficacy, resulting in the alleviation of symptoms and subsequent discharge. This case underscores the diagnostic challenges inherent in CRMO and sheds light on the potential of Meloxibell as an effective therapeutic agent. The successful outcome observed prompts consideration of Meloxibell as a valuable addition to CRMO management, warranting further research to elucidate its long-term efficacy and safety profile. As CRMO continues to pose diagnostic and therapeutic challenges, this case report contributes valuable insights to the evolving landscape of pediatric rheumatology, emphasizing the need for individualized treatment approaches in this complex disorder.
Medicine
Hamid Owaysee Osquee; Ali Reza Lotfi
Abstract
Examining laboratory parameters to determine acute or less severe cases of mucormycosis after contracting covid-19, identifying patients who are at higher risk of mortality, and increasing awareness for proper practice will be useful in improving the clinical situation. So we decided to Investigate Factors ...
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Examining laboratory parameters to determine acute or less severe cases of mucormycosis after contracting covid-19, identifying patients who are at higher risk of mortality, and increasing awareness for proper practice will be useful in improving the clinical situation. So we decided to Investigate Factors Affecting Mortality From mucormycosis After Covid-19 Infection. Methods: This study was a systematic review (Conducted by PRISMA guideline). This study was conducted in Tabriz university of medical sciences in 2022. Results: From examining the results of these studies (15 studies), it was found that mortality was higher in patients hospitalized in ICU and general wards, and a significant difference was observed between the average age of recovered and deceased patients. Having high blood pressure as well as diabetes mellitus also significantly led to an increase in mortality. Conclusion: Hospitalization in the intensive care unit, advanced age, high severity of covid-19, high blood sugar and underlying diseases significantly increase the risk of death due to mucormycosis following covid-19.
Medicine
Martin Viberman
Abstract
The process of hot extrusion of very fine cemented carbide powder with a combination of softener has been known for many years. This method has been successfully used for cermet’s to make simple prismatic shapes that have a large length to cross-sectional area ratio. Cylindrical and quadrangular ...
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The process of hot extrusion of very fine cemented carbide powder with a combination of softener has been known for many years. This method has been successfully used for cermet’s to make simple prismatic shapes that have a large length to cross-sectional area ratio. Cylindrical and quadrangular shapes and other sections can be easily made with this method, even making pipes is also possible. Depending on the plasticizer used (for example, polystyrene with the addition of dimethyl and diphenyl ether), the extrusion process requires temperatures between 160 and 175 degrees Celsius (320- and 350-degrees Fahrenheit). The process of complete and slow sticking under vacuum before full sintering is necessary and even vital to avoid stretching (from casting defects, from sagging), breaking or very small porosity. Twisting of bodies produced by extrusion similar to what happens in the plastic industry is acceptable for this process. In order to produce a high-quality product, hot pressing is necessary.
